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Adding yeast to poultry feed could reduce Salmonella

An active live yeast called Saccharomyces cerevisiae boulardii could improve food safety, reduce Salmonella colonization and boost intestinal health and maturity when added to poultry diets.

“I’ve been taking this kind of live active yeast and looking at the past, taking it all the way to the current and some recent new data on how this active yeast could potentially be a great tool for some forms of production,” Bill Potter, Ph.D., food safety technical advisor, Elanco, explained at the 2023 Poultry Tech Summit conference.

Saccharomyces cerevisiae boulardii was originally discovered in the quest to improve wine processing. In 1920, Henry Boulard traveled to IndoChina to search for new strains of yeast that can be used during the fermenting process. Unfortunately, this visit occurred at the same time as a cholera outbreak at the time. “He noticed that some of the natives in the area were going to certain plants, particularly the lychee fruit,” said Potter, noting that tea from this fruit provided relief from intestinal tract problems caused by the cholera. “As they say, the rest is history,” he added.

The active live yeast has three modes of action; impact on microbiome balance, improvement in natural defenses and improvement in gut integrity. One of the most unique characteristics of Saccharomyces cerevisiae boulardii is that it can sequester oxygen. In other words, it takes away oxygen that can otherwise by used by Salmonella, E. coli and other pathogens in the poultry gut, improving food safety.

In commercial trials, broilers supplemented with Saccharomyces cerevisiae boulardii showed significant reductions in pathogen colonization. Similar decreases in E. coli were seen in a layer operation during another study. Saccharomyces cerevisiae boulardii isn’t a silver bullet, Potter cautioned, but when the yeast is fed in combination with other management strategies, food safety can be improved.

Effects of meat consumption on human health

Meat has been and continues to be an important food source, delivering a wide range of valuable nutrients our bodies can easily absorb.

Along with other animal-source foods like fish, eggs and milk, it also plays an important role in several European cultural traditions and recipes. People are biologically adapted to a diet that includes meat, which is important in a healthy and balanced diet. Some nutrients in meat and other animal-source foods are not always easily obtained or obtainable from plant-based foods.

Meat is an excellent source of vitamins, minerals, and essential micronutrients the body can absorb easily. A 100g portion of red meat, for example, will provide around 25% of the recommended daily allowance for riboflavin, niacin, vitamins B5 and B6, and two-thirds for vitamin B12. Diets poor in animal-source foods can lead to various nutritional deficiencies. Studies have shown that low-meat diets may risk brain and reproductive system development. Indeed, it is recognised that animal-source foods are essential in an infant’s first 1,000 days of life and for the skeleton and brain development of pre-adolescents.

There are several important bioactive compounds in meat and processed meat products, such as vitamin B1, iron, zinc, choline, L-carnitine, conjugated linoleic acid (CLA), glutathione, taurine and creatine, which have been studied for their physiological properties. Conjugated linoleic acid, for example, has drawn significant attention in the last two decades for its biologically beneficial effects. CLA modulates immune and inflammatory responses and improves bone mass, while carnosine possesses strong antioxidant and anti-genotoxic activities, including the anti-ageing of cells.

From an evolutionary perspective, we have developed as omnivores, and meat has been a central component of our diet for millions of years. Claims about the health dangers of meat are not only improbable in the light of our evolutionary history, but they are also far from being supported by robust scientific evidence. The majority of evidence linking red and processed meat consumption with colorectal cancer and pathologies is observational and based on intakes of red and processed meat that exceed most European countries’ average intakes.

Interestingly, a study in the UK found similar rates of bowel/colorectal cancer in vegetarians and meat-eaters, suggesting that meat consumption in general isn’t a major cause of this disease. The correlation between food, meats and cancer is very difficult to study because there are many elements, real or perceived, that may favour the onset and the development of cancer. National authorities have based recommendations on the studies developed by the International Agency for Research Studies on Cancer (IARC) that highlight and classify the considered agents that are certainly or presumably responsible for cancer onset.

“Carcinogenic” is the term given to something that can cause cancer. The problem, in terms of communication to the public, is in the verb “to cause”. It is not possible to give a determined cause-effect interpretation in this instance. In other words, it is not possible to say, “If you eat processed meat, then you will surely get colorectal cancer”. In the same way, it is not possible to say that if someone is exposed to a carcinogenic agent, they will certainly get cancer. Scientists hold to the premise that “carcinogenic” is something that, taken in certain doses and for a certain period, can increase the risk of developing a certain type of cancer throughout life. However, when such information is shared with the general public, the interpretation is often that if a substance or a food is carcinogenic, it most certainly causes cancer.

A consequence of this miscommunication is that some people will believe that if we do not eat a specific food or something with a carcinogenic substance, then surely we are safe from cancer. Unfortunately, this is not true. We may get, and statistically it happens, lung cancer even if we do not smoke and colon cancer even if we are strictly vegan. No one can say with certainty whether, even eating processed meat every single day, we will get colorectal cancer or not. But this does not mean that eating a certain food or not eating it would expose someone to the same risk.

Going back to the IARC monography, the various agents are not classified based on how carcinogenic they are, nor does the report deal with estimating the risk, individual or collective, of an exposure to a given agent once established to be carcinogenic. This means it is incorrect to treat all carcinogenic agents in the same way. Stating that “processed meat is like smoking or asbestos” is deeply wrong, and certainly, it pays no service to public opinion or knowledge. Carcinogenic agents are different, but it is not the IARC’s task to classify this aspect. There is also an interesting point regarding the consumption amounts investigated by the IARC, which are 50 grammes of processed meat or 100 red meat per day. This level of consumption is much higher than that of European consumers and, in general, of the rest of the world. For all these reasons, meat and processed meat products can be safely consumed as a part of healthy and balanced diets, but the most important thing for authorities to keep in mind is to communicate these concepts clearly and properly.

WOAH warns global pig industry of sub-standard ASF vaccines

The World Organisation for Animal Health (WOAH) is warning veterinary authorities and the global pig industry against the use of non-compliant and poor-quality vaccines for African swine fever (ASF). In a statement issued October 18, WOAH stressed the importance of the use of only high-quality ASF vaccines with proven efficacy and safety, and which have been subject to regulatory evaluation and approval in accordance with WOAH international standards.

“The research community has been working to develop an effective vaccine and recent announcements of modified live vaccines being approved or tested in some countries have raised hopes for the availability of new effective tools to contain the ASF epidemic,” WOAH said. The use of non-compliant and poor-quality vaccines may not confer any protection against ASF and risks spreading vaccine viruses that could result in acute or chronic disease, WOAH said. Additionally, these vaccine viruses could also recombine with field strains to generate novel strains. The world’s first ASF vaccines were authorized by Vietnam in July, when two vaccines were cleared for domestic use in pigs in the country.

Approval came after widespread testing in the country’s swine herds. The government reported the vaccines to be 95% effective. The vaccines – NAVET-ASFVAC (from Navetco National Veterinary Joint Stock Co.), and the AVAC ASF LIVE vaccine (from AVAC) — were jointly developed by U.S. scientists with two different commercial partners in Vietnam. In some other Asian countries, registration of the AVAC vaccine is underway. A third vaccine, DACOVAC-ASF2 vaccine from the Dabaco Group, is reportedly under evaluation in Vietnam. In the Philippines, applications are under consideration for the importation of four ASF vaccines. A Phase 1 trial was completed in May, and three farms in different provinces have been selected as the locations of Phase 2 field trials, the source reports. Authorities are awaiting complete documentation from a second vaccine company. In order to bring to an end the country’s four-year battle to eliminate ASF, the government has allocated PHP1.5 billion ($26.4 million) for the vaccination of the nation’s hogs.

Iran to produce feedstuff from lignocellulosic waste

A group of Iranian scientists have developed a method for processing lignocellulosic waste into nitrogen-rich animal feed. They claimed that this is the first-of-its-kind technology in the global feed industry. Around 21.5 million tons of lignocellulosic residues from straw are produced per year in Iran, Dr Kian Mehr, one of the chief researchers, said. These are inexpensive and abundant sources of fibre, though their use in the feed industry traditionally has been limited by low digestibility. Solving this issue has tremendous practical importance for Iran, which currently heavily depends on the import of feedstuff.

The scientists said they used nitrogen enrichment and oxidation to improve the digestibility of lignocellulosic biomass, though no additional details have been provided. A series of preliminary trials have shown that the biomass processed using the developed technology, when added to the cattle feed, also lowers methane emissions by a solid 67%. The processing takes little time, requires ambient temperature and pressure, and can be used on a wide range of biomass in a solid state without a need to recover chemicals in advance, Dr Mehr stated, speaking about the upsides of the developed method. In addition, it is almost waste-free and is not associated with the generation of any toxic by-products. The lignocellulosic waste is also good for the production of feed pellets, thanks to the high content of lignin, which is used as a natural binder. In theory, the scientists, said using lignocellulosic waste as a feed component feed manufacturers could save money on energy costs, and require less binders. On the other hand, it looks like the technology is relatively far from commercialisation. So far, the lignocellulosic waste processing has taken place only in laboratory conditions. The researchers believe they still have to shape up their method before it could be offered for mass production.

Synthetic cattle urine used in fight against malaria

Each year, more than 200 million people suffer from malaria around the world, and every two minutes a child dies from the disease. The disease is most common in poor areas and is itself a contributing factor to poverty: a sick person cannot perform his or her daily tasks, which can lead to a loss of income for the household. At the societal level, the healthcare system and the economy of countries, where malaria is endemic, are affected. At the Swedish University of Agricultural Sciences (SLU), the fight against malaria continues through novel research on how to control and trap the mosquitoes that carry the malaria parasite. As there is currently no effective vaccine available to prevent malaria, controlling the mosquitoes that spread the parasite is imperative for preventing the spread of the disease. However, the existing techniques for indoor malaria mosquito control have been put to the test, due to the development of pesticide resistance in mosquito populations and behavioral changes in the mosquitoes. As a result, there are now more people being bitten outdoors. Therefore, there is an urgent need for innovative control methods that complement the current strategies and specifically focus on mosquitoes that are active outdoors. Outdoor-based traps can be substantially more efficient when baited with synthetic human and animal odours. For example, it has been demonstrated that cattle urine attracts many blood sucking insects, in various physiological stages and different species of mosquitoes. Adult female malaria mosquitos use the urine as a supplementary nitrogen–rich meal, enhancing flight mobility, survival and reproductive traits. Researchers from SLU took this into account when they initially developed a synthetic cattle urine odour to lure malaria mosquitoes into traps. During one year, the researchers collected seasonal information on the malaria mosquito species populations along with data on the presence and prevalence of malaria in mosquitoes and humans. At the onset of the second year, they installed 50 traps baited with the synthetic cattle urine odour, powered by solar panels, in one of the villages and continued collecting entomological and parasitological data. By mass trapping, they were able to reduce the population of malaria mosquitoes by up to 70% and malaria prevalence by up to 60%, despite a major malaria epidemic affecting the region, said Professor Rickard Ignell, Department of Plant Protection Biology, SLU.

Digital radiography solution could transform poultry breeding

A fast, safe method of analysing bone density in live hens could help poultry producers select the optimum birds with which to breed, to improve animal health and welfare. Scientists at the Roslin Institute have developed a digital X-ray procedure that takes around 45 seconds to conduct, is practical for hens and poultry workers, and delivers reliable, reproducible results.

Their novel method presented in British Poultry Science enables breeders to consider bone density in their selection of laying hens, which are at risk of fractures from biological changes linked with laying eggs. Recent advances in digital X-ray technology have enabled researchers to develop their technique to capture and interpret images relating to bone density. Their method involves quickly capturing digital X-rays of live hens, from which their leg bone density can be calculated, and data digitally shared. Researchers optimised their method to ensure a clear image in minimal exposure time. Their approach was validated by comparing results from chicken X-rays with those from analysis of chicken leg bones.

The procedure, which takes about 45 seconds, offers a fast, practical alternative to conventional imaging techniques such as Dual-energy X-ray Absorptiometry, Digitised Fluoroscopy and CT scans. Strong bones offer improved health and reduced risk of fractures in birds that have freedom to move around their environment. The keel bone, or sternum, of hens is particularly prone to damage and previous research by the same team has shown that leg bone density is genetically related to that of the keel bone, and to fracture risk. The new practical way to measure bone density also has animal welfare implications, as it could help reduce the number of animals needed for research into nutritional and management aids for bone health.

Escalation of the Gaza conflict will have profound, biting and worldwide impact

Rabobank, assessing the impact of the conflict in Israel on food, energy, and fertilizer trends, says that if it is contained to the Israel and Gaza region it may not move the needle too much for energy, commodity or livestock prices. Mike Every, Rabobank’s global strategist and geopolitics expert, and Stefan Vogel, general manager RaboResearch for Australia and New Zealand, discussed the current situation in the Middle East and its potential impact for farmers in a podcast this week. If Israel moves into Gaza, and initiates a ground offensive, there is a very high probability that the Iranian backed and funded militia, Hezbollah, based in south Lebanon, would open fire on Israel and start a two-front war (these two steps have already been taken – ed.). And were that to happen, it is extremely likely that other Iranian backed forces such as militias in Yemen, in Iraq, and in Syria would also move towards the border and open fire with whatever missile forces they have. [In such a scenario] it is naive to think Iran would not press other buttons it has available at its disposal which would include trying to whip up an uprising in the West Bank and potentially even amongst Israeli Arabs.

Eventually, the conflict could spread even further, developing into a broad regional war with no easy resolution on top of the world’s major energy reserves. Oil and diesel prices would soar in such an escalation of the conflict, with oil potentially rising to $150 per barrel. “In a nutshell, if we get into that scenario, it is akin to what we saw in the 1970s after the Yom Kippur war when the Arab economies decided to restrict flows of oil to the US, and then again in 1979 after we had the Iranian revolution and the hostage crisis, when Iran did the same thing. The economic effects would be deep, biting and felt worldwide,” warned Every.

The geopolitical expert is worried about the propensity for the dominos to topple much quicker than commentators are currently predicting, as fear about security in Israel is climbing rapidly. He also outlined how there may be an incentive for other global powers such as China and Russia to support Iran and try and humiliate the US and Israel in the Middle East region, keep them bogged down in a big war, distract the US from Ukraine and also from its military build-up in East Asia to protect Taiwan. “This is not a forecast, but it is a worryingly logical set of events which, if they were to transpire, would happen faster than you think.” The implications, evidently, of such escalation of the war for the food, agriculture, and energy markets would be quite devastating.

First complete corn genome map created

In a groundbreaking achievement, scientists, led by University of Nebraska–Lincoln researcher James Schnable, have successfully mapped the complete genome of corn. This milestone development promises to revolutionize the future of agriculture, offering invaluable insights into crop health, resilience, and productivity. Published recently in the prestigious journal Nature Genetics, the study represents a significant leap forward in the field of genetics, coming on the heels of the human genome’s complete mapping just a year ago. The corn genome, due to its sheer size and complexity, has long posed a formidable challenge for scientists seeking to decode its genetic makeup.

Over the years, technology has made strides in this area, with the first draft of the corn genome emerging in 2009. However, numerous gaps remained, comprising over 100,000 unresolved genetic sequences. James Schnable, the Charles O. Gardner Professor of Agronomy, explained, “Our team drew on the latest technology, plus the particular expertise of the individual team members, and that finally made possible the mapping of the complete corn genome.” A significant aspect of this achievement was the resolution of complex genetic regions containing nearly identical paralogs – genes that are so similar they were previously indistinguishable. Corn’s genetic repetition presents an extraordinary challenge, with vast stretches of genetic material intermingled, making it difficult to pinpoint individual gene functions.

The fully sequenced corn genome holds immense potential for developing improved corn varieties by enhancing the understanding of how genetic differences influence traits. Schnable explained, “Rather than conducting selection, we will have the potential to design and engineer corn varieties to adapt to changing climates and grow in more nitrogen-limited conditions.” Now that the corn genome is fully sequenced, scientists can embark on essential follow-up research to study and understand the function of individual genes previously unidentified. Schnable emphasized the university’s advantage in this endeavor, given its robust research and Extension network and the ability to grow corn varieties across a wide range of environments.

Environmental and dam risks of Johne’s Disease

Johne’s Disease or paratuberculosis is a chronic disease of ruminants which is responsible for large economic losses in the dairy sector. The disease is caused by Mycobacterium avium subspecies paratuberculosis (MAP), which typically infects calves that remain latently infected during a long period, making early detection of infection especially challenging. Cow-to-calf transmission can occur in-utero via milk/colostrum or faecal-orally, so understanding the different transmission routes to calves is important in informing control recommendations. The aim of a longitudinal study carried out by researchers at the Royal Veterinary College was to measure the association between the transmission routes via the dam and the environment on a calf that subsequently tested serologically positive for MAP. The study comprised of 439 UK dairy calves from 6 herds enrolled between 2012 and 2013. These calves were followed from birth until 2023. Individual calf data was captured at birth. During follow-up, individuals entering the milking herd were quarterly tested for the presence of MAP antibodies using milk ELISA. Cox regression models were used to measure the association between exposure from the dam (in-utero and/or colostrum) or from the environment (long time in dirty yard) and time to first detection of MAP infection. In conclusion, the researchers found that: 1) Map infection risk is partly driven by the dam’s infection status. 2) Calves from infected dams have higher MAP infection risk, regardless of the dam’s test status at calving. 3) Spending prolonged time in a dirty yard increases the risk of MAP infection. 4) The dam’s impact on MAP risk extends beyond colostrum transmission. 5) MAP persistence in commercial dairy herds results from a combination of dam-related and environment-related factors.

Remarkable progress in sourcing soy responsibly in Europe

Results published in the European Soy Monitor 2021, points to 40% of soybean meal equivalent of total European soy consumption to be sourced according to the FEFAC Soy Sourcing guidelines and 24% certified deforestation-free soy. The report also refers to FEFAC’s initial risk assessment which estimates that just under 94% of EU soy imports were sourced from low-deforestation regions, based on EU trade statistics and industry expert assessments. The figures show good progress continues to be made. Since the publication of the first European Soy Monitor of 2018 estimations, the provisional data for 2021 indicates that FEFAC members reported an increase of 21% over the past 3 years. However, the 40% figure was slightly lower than the 43.8% recorded in 2020. Pedro Cordero, FEFAC president, welcomed the latest figures: “I am pleased with the continued positive trend that the European feed sector and its supply chain partners have been able to display as regards the industry’s use of responsible soy. FEFAC’s internal estimates indicate that a significant part of soy used in the EU in 2021 came from regions with low deforestation risk, including the EU, United States, Canada and Ukraine. These sources are considered “deforestation-free”, although not officially certified as such. The soybean trade itself has remained relatively unaffected. Brazil and the United States continue to be the world’s biggest producers and China by far the biggest soy consuming country. European soy production increased from 2.68m tonnes in 2020 to 2.71m in 2021.